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Left ventricular ejection fraction (LVEF) 1 has persisted as the primary measure of left ventricular systolic function despite flaws in this approach. Patients with heart failure are relieved when the LVEF is reported as normal, and clinicians may use the report of a depressed LVEF to persuade patients of the need for treatment.Patients with hypertrophic cardiomyopathy may have labile left ventricular (LV) outflow tract gradients. If septal reduction therapy is to be considered, there must a gradient of >50 mm Hg either at rest or during provocation.
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